Cardiology

05/08/2014 - 10:48

It is widely accepted that heart muscle cells in mammals stop replicating shortly after birth, limiting the ability of the heart to repair itself after injury. A study published by Cell Press May 8th in the journal Cell now shows that heart muscle cells in mice undergo a brief proliferative burst prior to adolescence, increasing in number by about 40% to allow the heart to meet the increased circulatory needs of the body during a period of rapid growth. The findings suggest that thyroid hormone therapy could stimulate this process and enhance the heart's ability to regenerate in patients with heart disease.

 

05/02/2014 - 10:22

It’s about the size of a large vitamin pill and, for the first time in Ohio, the smallest heart pacemaker available is being tested at The Ohio State University Wexner Medical Center. Doctors at Ohio State’s Richard M. Ross Heart Hospital recently implanted the tiny device in a Columbus woman as part of a global clinical trial to test its safety and effectiveness.  Unlike conventional pacemakers, which require a chest incision and electrical leads that run through a vein to the heart, this device is wireless and is threaded through a catheter, then attached directly to the heart muscle.

 

04/30/2014 - 13:55

Numerous studies have suggested a relationship between cardiovascular disease risk factors and prostate cancer. A new study by researchers at the University of California, San Diego School of Medicine, with colleagues in Norway, significantly refines the association, highlighting genetic risk factors associated with low density lipoprotein (LDL) cholesterol and triglycerides as key players and identifying 17 related gene loci that make risk contributions to levels of these blood lipids and to prostate cancer.

 

04/24/2014 - 12:00

Scientific research at UT Southwestern Medical Center previously discovered that the newborn animal heart can heal itself completely, whereas the adult heart lacks this ability. New research by the same team today has revealed why the heart loses its incredible regenerative capability in adulthood, and the answer is quite simple – oxygen.

 

04/03/2014 - 14:40

Combating the tissue degrading enzymes that cause lasting damage following a heart attack is tricky. Each patient responds to a heart attack differently and damage can vary from one part of the heart muscle to another, but existing treatments can’t be fine-tuned to deal with this variation.

 

04/02/2014 - 21:48

The mammalian heart has generally been considered to lack the ability to repair itself after injury, but a 2011 study in newborn mice challenged this view, providing evidence for complete regeneration after resection of 10% of the apex, the lowest part of the heart. In a study published by Cell Press in Stem Cell Reports on April 3, 2014, researchers attempted to replicate these recent findings but failed to uncover any evidence of complete heart regeneration in newborn mice that underwent apex resection.