Genetics

06/20/2014 - 12:08

 Cancers driven by – and dependent on – the potent mutated cancer gene KRAS have an especially poor prognosis, and three decades of scientific attempts have failed to produce drugs that can attack KRAS and halt the tumors’ runaway growth.

06/09/2014 - 12:32

 New genomic research led by UC San Francisco scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas.

06/04/2014 - 17:26

Interaction of the monoamine oxidase A genotype with childhood adversity is predictive of crime rates in a group of incarcerated men. This is the main finding of a new study from researchers in Sam Houston State University published in the journal Psychiatric Genetics.

 

05/13/2014 - 09:08

Whitehead Institute scientists have identified a genetic cause of a facial disorder known as hemifacial microsomia (HFM). The researchers find that duplication of the gene OTX2 induces HFM, the second-most common facial anomaly after cleft lip and palate.

 

05/09/2014 - 09:44

Scientists at The Scripps Research Institute (TSRI) have engineered a bacterium whose genetic material includes an added pair of DNA “letters,” or bases, not found in nature. The cells of this unique bacterium can replicate the unnatural DNA bases more or less normally, for as long as the molecular building blocks are supplied.

 

05/09/2014 - 09:20

Helicosporidium is a lethal parasite of insects including caterpillars, beetles and blackflies. The evolutionary origins of this parasite have remained shrouded in mystery but recent studies strongly suggested similarity to a green alga called Prototheca. Evolution of parasites from algae is not unheard of. One of the most famous examples is the transition of the malaria parasite Plasmodium from red algae, with loss of genes encoding biological functions that are no longer needed in the organism’s new life as a parasite.