Heart

04/07/2014 - 08:09

Motor neuron disease or central nervous system injury can lead to loss of essential voluntary muscle activity such as speaking, walking, breathing, and swallowing due to defects in motor neurons. A new study published on 4th April in the journal Science describes a method for bypassing the defective central motor circuit using engrafted, light-activated motor neurons. The study in mice was led by researchers in University College London (UCL) and King’s College London and offers hope for treatment of paralysis and breathing difficulties in these devastating conditions.

 

04/03/2014 - 14:40

Combating the tissue degrading enzymes that cause lasting damage following a heart attack is tricky. Each patient responds to a heart attack differently and damage can vary from one part of the heart muscle to another, but existing treatments can’t be fine-tuned to deal with this variation.

 

04/02/2014 - 21:48

The mammalian heart has generally been considered to lack the ability to repair itself after injury, but a 2011 study in newborn mice challenged this view, providing evidence for complete regeneration after resection of 10% of the apex, the lowest part of the heart. In a study published by Cell Press in Stem Cell Reports on April 3, 2014, researchers attempted to replicate these recent findings but failed to uncover any evidence of complete heart regeneration in newborn mice that underwent apex resection.

 

03/17/2014 - 08:51

A gene termed TM6SF2 has been identified as important in affecting cholesterol levels and myocardial infarction in a new study published as an advanced online publication in Nature Genetics. The study, from scientists in Norway and in the University of Michigan offers a promising new drug target in cardiovascular disease.

 

03/14/2014 - 09:39

Large waist circumference leads to lower life expectancy even among people with healthy body mass index (BMI) according to the results of a new study in Mayo Clinic Proceedings. The study from researchers in the USA, Australia, Sweden, Norway and Finland found a linear association between waist circumference and all-cause mortality.

 

02/27/2014 - 11:00

You might think building muscle is a good thing, but that's often not so in the case of blood vessels in adults. In fact, excess smooth muscle is a root problem in many vascular diseases, as it causes arteries to constrict and blood pressure to rise. Now, an in-depth analysis of arterioles in mice with pulmonary hypertension explains how those misplaced smooth muscle cells develop.