04/22/2012 - 11:45

Japanese researchers found, using an animal model, that the anti-hypertensive drug, moxonidine, which acts on the imidazoline receptors in the cardiovascular center of the brainstem can improve heart function and survival independent of its effect on blood pressure. They also found that moxonidine had a favorable effect on oxidative stress, which is related to insulin resistance, the underlying abnormality in diabetes, which is common in people with heart failure.