Sigma-1 receptor

06/20/2012 - 14:44

Researchers from Boston University School of Medicine (BUSM) have demonstrated in experimental models that blocking the Sigma-1 receptor, a cellular protein, reduced binge eating and caused binge eaters to eat more slowly. The research, which is published online in Neuropsychopharmacology, was led by Pietro Cottone, PhD, and Valentina Sabino, PhD, both assistant professors in the pharmacology and psychiatry departments at BUSM.

09/21/2011 - 19:59

A new report suggests that defect in a protein is the cause of amyotrophic lateral sclerosis (ALS) in juvenile onset patients.  This protein could be a target for ALS therapy.  The authors studied an extended family with multiple members diagnosed with the juvenile form of the disorder  and discovered the genetic defect in a protein called sigma-1 receptor.