aging

04/17/2014 - 16:57

Researchers at the University of California, San Diego School of Medicine report that older women, plucky individuals and those who have suffered a recent major loss are more likely to be compassionate toward strangers than other older adults.

 

04/01/2014 - 16:00

Approximately 50% of elderly humans experience sleep disorders, with consequences for quality of life and poor health. However, a new study on the fruit fly Drosophila melanogaster suggests that manipulation of the nutrient sensing insulin/IGF (IIS) and TOR (Target of Rapamycin) signalling networks eases age-related decline in sleep quality and duration. The study from researchers at the Max Planck Institute (MPI) for Biology of Ageing in Cologne is published on April 1st in the journal PLoS Biology.

 

03/04/2014 - 11:00

While it's clear that diet can affect longevity, there's great uncertainty about which combinations of foods are best for attaining a long and healthy life. Now two groups of researchers publishing in the March 4 issue of the Cell Press journal Cell Metabolism each suggest that low protein intake may be a key factor, at least until old age.

 

02/27/2014 - 09:53

Activating a protein called sirtuin 1 extends lifespan, delays the onset of age-related metabolic diseases, and improves general health in mice. The findings, which appear online February 27 in the Cell Press journal Cell Reports, point to a potentially promising strategy for improving health and longevity.

 

12/20/2013 - 15:16

As mice age, cells in tissues such as the liver and skeletal muscle lose control over rogue sequences of DNA called “retrotransposable elements,” according to new research in the journal Aging. The elements, which may undermine health, could proliferate in old mice and were also abundant in cancerous tissue. A low-calorie diet, however, restrained their advance.

 

12/16/2013 - 10:14

The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive impairment (MCI), suggesting that BACE1 activity is important for conversion of mild cognitive impairment to AD and may be an early indicator of AD. The results are published in the January issue of The American Journal of Pathology.