08/07/2012 - 13:43

In order to treat acute megakaryoblastic leukemia (AMKL) in patients who do not respond to current therapies, researchers need a protein target at which to take aim. A new effort at the Broad Institute draws on the strengths of a large number of the Broad’s resources and platforms to identify such targets and narrow in on suitable drugs to pursue them. The study of AMKL has been one of the first projects to which this highly integrated approach has been applied, and findings point to the potential of a drug candidate currently under clinical investigation for the treatment of other forms of cancer.