amyloid-beta

06/19/2013 - 09:24

A new finding suggests that the progression of Alzheimer's disease worsened with the increased interaction of two proteins. The interaction between the phosphorylated tau and the amyloid-beta in its toxic form at the synapses has damaging effects which could lead to cognitive decline.

11/16/2012 - 14:09

Last March, researchers at UCLA reported the development of a molecular compound called CLR01 that prevented toxic proteins associated with Parkinson's disease from binding together and killing the brain's neurons.  Building on those findings, they have now turned their attention to Alzheimer's disease, which is thought to be caused by a similar toxic aggregation or clumping, but with different proteins, especially amyloid-beta and tau.

04/23/2012 - 15:37

According to a new study, the neuron-killing pathology of Alzheimer’s disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau.