12/15/2011 - 12:07

An amide is an organic compound containing a carbonyl group (R-C=O) linked to a nitrogen atom (N).  The bonds in an amide are notoriously difficult to break: reaction times under mild, neutral-pH conditions are over 100 years.  The only way to make amide bonds break down faster without resorting to acids, bases, and catalysts is to twist them physically.