bipolar disorder

03/24/2014 - 10:45

Persons with bipolar disorder, previously referred to as manic depressive illness, are more likely than others to possess superior leadership skills at an early age. The same is true for their siblings, and later in life siblings are overrepresented in professional leadership roles, especially in politics. This has been shown in a new doctoral thesis from Karolinska Institutet.


09/05/2013 - 09:08

The American Psychiatric Association has introduced the fifth iteration of the psychiatric diagnostic manual, DSM-V, representing the current best effort of the brightest clinical minds in psychiatry to categorize the enormously complex pattern of human emotional, cognitive, and behavioral problems. On the other hand, in new and profound ways, neuroscience and genetics research in psychiatry are yielding insights that challenge the traditional diagnostic schema that have long been at the core of the field.


08/12/2013 - 10:38

In a new large-scale study, a worldwide research consortium show that people susceptible to psychiatric disorders such as depression, schizophrenia and bipolar disorder have underlying genetic similarities. Several research groups from Karolinska Institutet took part in the study, which is published in the scientific periodical Nature Genetics.


07/26/2013 - 14:13

Bipolar disorder evolves differently in patients who also binge eat, a study by Mayo Clinic, the Lindner Center of HOPE and the University of Minnesota found. Binge eating and obesity often are present among bipolar patients, but the mood disorder appears to take a different path in those who binge eat than it does in obese bipolar patients who do not, the researchers discovered. The findings are published online in the Journal of Affective Disorders


05/24/2013 - 07:13

A new study from Karolinska Institutet reveals that lithium treatments for bipolar disorder can sometimes increase the length of so-called telomeres, the sections of DNA at the end of the chromosomes in the cell nucleus. The shortening of these telomeres has been linked to ageing, stress and mental disease, and the researchers now hope that their results will mark the first step on the path to a more individualised treatment of bipolar disorder.


03/07/2013 - 10:43

Researchers at Karolinska Institutet have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis. The study, which is published in the scientific periodical Molecular Psychiatry, identifies a gene variant associated with an increased production of KYNA.