03/17/2014 - 08:51

A gene termed TM6SF2 has been identified as important in affecting cholesterol levels and myocardial infarction in a new study published as an advanced online publication in Nature Genetics. The study, from scientists in Norway and in the University of Michigan offers a promising new drug target in cardiovascular disease.


02/28/2014 - 10:18

Early but not advanced forms of atherosclerotic plaques in the vessel wall disappear when the levels of ‘bad’ cholesterol are lowered, according to a study in mice from Karolinska Institutet, Sweden. The findings, published in  PLoS Genetics , indicate that preventative cholesterol-lowering treatment could prevent more advanced, clinically relevant plaque to develop.


12/09/2013 - 10:15

High-density lipoprotein (HDL), known colloquially as "good cholesterol", protects against dangerous deposits in the arteries. An important function of HDL is its anti-inflammatory properties. An international research team at the Institute of Innate Immunity at the University Hospital of Bonn and the LIMES Institute at the University of Bonn has identified a central switch by which HDL controls the inflammatory response. The results are presented in the current issue of "Nature Immunology".


11/07/2013 - 15:21

A team of researchers at UT Southwestern has found that as cholesterol is metabolized, a potent stimulant of breast cancer is created – one that fuels estrogen-receptor positive breast cancers, and that may also defeat a common treatment strategy for those cancers.


09/11/2013 - 12:40

The largest DNA-sequencing study of anorexia nervosa has linked the eating disorder to variants in a gene coding for an enzyme that regulates cholesterol metabolism. The finding suggests that anorexia could be caused in part by a disruption in the normal processing of cholesterol, which may disrupt mood and eating behavior.


06/07/2013 - 18:01

A typical American consumes approximately 3 or more tablespoons of vegetable oil each day. Vegetable oils, like those from soy, corn and canola, are a significant source of calories and are rich in linoleic acid (LA), which is an essential nutrient. Since the 1970s, researchers have known that LA helps reduce blood cholesterol levels, and for decades, scientists have known that consuming LA can help lower the risk of heart disease.