Researchers at the University of California, Santa Cruz, are developing new microscope technologies to enable biologists to see deep within living tissues and observe critical processes involved in basic biology and disease. Principal investigator Joel Kubby, an associate professor of electrical engineering in the Baskin School of Engineering at UCSC, has worked on adaptive optics (AO) systems for large telescopes as well as for biological imaging. In astronomy, AO systems correct the blurring of telescope images caused by turbulence in the Earth's atmosphere. In microscopy, blurring is caused by the flowing cytoplasm of living cells.