morphine

How morphine increases pain in some people - a new pathway to reduce pain identified
01/06/2013 - 21:32

New research suggests that adults and children whose pain gets worse when treated with morphine may be closer to a solution. For individuals with agonizing pain, it is a cruel blow when the gold-standard medication actually causes more pain. 

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Researchers find mechanism of opiate addiction is completely different from other drugs
10/05/2012 - 14:16

Chronic morphine exposure has the opposite effect on the brain compared to cocaine in mice, providing new insight into the basis of opiate addiction, according to Mount Sinai School of Medicine researchers. They found that a protein called brain-derived neurotrophic factor (BDNF), which is increased in cocaine addiction, is inhibited in opioid addiction.

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Study shows heroin, morphine addiction can be blocked
08/15/2012 - 11:22

In a major breakthrough, an international team of scientists from the University of Adelaide and University of Colorado Boulder has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

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Few regular users of strong painkillers
07/30/2012 - 07:57

Fewer Norwegians than suspected take opioids such as Paralgin forte and morphine regularly. Those who do, however, use these strong painkillers over extended periods. Each year roughly 10 per cent of the Norwegian population are given a prescription for opioids. Until recently, the number of these who can be considered regular users of such medications was unknown.

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Discovery paves way for improved pain-killers
04/03/2012 - 12:24

An international team of researchers involving the University of Adelaide has made a major discovery that could lead to more effective treatment of severe pain using morphine. Morphine is an extremely important drug for pain relief, but it can lead to a range of side-effects - such as patients developing tolerance to morphine and increased sensitivity to pain. Until now, how this occurs has remained a mystery.

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Caltech Chemists Devise Chemical Reaction that Holds Promise for New Drug Development
01/13/2012 - 12:32

A team of researchers at the California Institute of Technology (Caltech) has devised a new method for making complex molecules. The reaction they have come up with should enable chemists to synthesize new varieties of a whole subclass of organic compounds called nitrogen-containing heterocycles, thus opening up new avenues for the development of novel pharmaceuticals and natural products ranging from chemotherapeutic compounds to bioactive plant materials such as morphine.

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