09/12/2013 - 09:18

Using large and frequent doses of the pain-killer codeine may actually produce heightened sensitivity to pain, without the same level of relief offered by morphine, according to new research from the University of Adelaide. Researchers in the Discipline of Pharmacology have conducted what is believed to be the world's first experimental study comparing the pain relieving and pain worsening effects of both codeine and morphine.


01/06/2013 - 21:32

New research suggests that adults and children whose pain gets worse when treated with morphine may be closer to a solution. For individuals with agonizing pain, it is a cruel blow when the gold-standard medication actually causes more pain. 

10/05/2012 - 14:16

Chronic morphine exposure has the opposite effect on the brain compared to cocaine in mice, providing new insight into the basis of opiate addiction, according to Mount Sinai School of Medicine researchers. They found that a protein called brain-derived neurotrophic factor (BDNF), which is increased in cocaine addiction, is inhibited in opioid addiction.

08/15/2012 - 11:22

In a major breakthrough, an international team of scientists from the University of Adelaide and University of Colorado Boulder has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

07/30/2012 - 07:57

Fewer Norwegians than suspected take opioids such as Paralgin forte and morphine regularly. Those who do, however, use these strong painkillers over extended periods. Each year roughly 10 per cent of the Norwegian population are given a prescription for opioids. Until recently, the number of these who can be considered regular users of such medications was unknown.

04/03/2012 - 12:24

An international team of researchers involving the University of Adelaide has made a major discovery that could lead to more effective treatment of severe pain using morphine. Morphine is an extremely important drug for pain relief, but it can lead to a range of side-effects - such as patients developing tolerance to morphine and increased sensitivity to pain. Until now, how this occurs has remained a mystery.