neurodevelopment

02/28/2014 - 10:26

Males are at greater risk for neurodevelopmental disorders, such as autism spectrum disorder (ASD), than females, but the underlying reasons have been unclear. A large cohort study published by Cell Press on February 27th in the American Journal of Human Genetics provides compelling evidence in support of the ”female protective model,” which proposes that females require more extreme genetic mutations than do males to push them over the diagnostic threshold for neurodevelopmental disorders.

 

12/05/2013 - 07:50

Mice whose mothers suffered from infection or inflammation during pregnancy are at greater risk for developing behaviors similar to those seen in people with autism spectrum disorders (ASD). Now, researchers reporting in the Cell Press journal Cell on December 5 have linked those neurodevelopmental symptoms in the mice to changes in the bacteria living in the animals' guts. What's more, when researchers treated those animals with bacteria found in the healthy gut, a number of behavioral abnormalities including anxiety-like behavior largely went away.

 

07/10/2013 - 07:09

Sensory processing disorders (SPD) are more prevalent in children than autism and as common as attention deficit hyperactivity disorder, yet it receives far less attention partly because it’s never been recognized as a distinct disease. In a groundbreaking new study from UC San Francisco, researchers have found that children affected with SPD have quantifiable differences in brain structure, for the first time showing a biological basis for the disease that sets it apart from other neurodevelopmental disorders.

 

07/01/2013 - 14:06

Researchers have pinpointed the role of a gene known as Arl13b in guiding the formation and proper placement of neurons in the early stages of brain development. Mutations in the gene could help explain brain malformations often seen in neurodevelopmental disorders.

 

10/11/2012 - 11:07

Babies born prematurely to low-income parents have a disproportionately high risk for developing dangerous brain bleeds that require multiple surgeries and extensive follow-up, according to a small Johns Hopkins Children's Center study.

06/04/2012 - 08:22

One of the largest studies to investigate birth complications and later mental health has found that premature birth constitutes a single, independent risk factor for a range of severe psychiatric disorders. Researchers at King's College London in the UK and Karolinska Institutet suggest that neurodevelopmental differences in those born prematurely may be important in understanding the link.