tissue plasminogen activator

10/01/2013 - 15:46

A telestroke service increases the rate of effective tissue plasminogen activator (tPA) therapy for patients with acute ischemic stroke treated at community hospitals, according to a report in the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

 

10/17/2011 - 09:43

The only medication currently approved for stroke treatment – tissue plasminogen activator (tPA), which dissolves blood clots – is associated with an increased risk of bleeding in the brain, particularly among patients with hyperglycemia (high blood sugar). A study led by Raymond A. Swanson, MD, chief of the neurology and rehabilitation service at the San Francisco VA Medical Center, provides a possible reason: high blood sugar fuels the formation of superoxide, a toxic form of oxygen, which in turn damages tissues, weakens blood vessels and promotes excess bleeding.