rheumatoid arthritis

02/26/2014 - 11:07

A new study suggests that vitamin D deficiency in older adults leads to compromised immune function. This results in increased risk of diseases including cardiovascular disease and rheumatoid arthritis. The study, accepted for publication in the Journal of Clinical Endocrinology & Metabolism, was carried out by researchers in the University of Ulster in Northern Ireland, UK and Trinity College and St. James’s Hospital, both in Dublin, Ireland.

 

05/08/2013 - 10:06

Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide.

 

04/22/2013 - 09:41

A new study, published in the open access journal Arthritis Research & Therapy, shows that smoking just a few cigarettes a day more than doubled the risk of rheumatoid arthritis (RA). To give up smoking decreases the risk, but compared to people who have never smoked this risk is still elevated 15 years after giving up.

 

01/22/2013 - 09:55

In one of the first genome-wide studies to hunt for both genes and their regulatory “tags” in patients suffering from a common disease, researchers have found a clear role for the tags in mediating genetic risk for rheumatoid arthritis (RA), an immune disorder that afflicts an estimated 1.5 million American adults. By teasing apart the tagging events that result from RA from those that help cause it, the scientists say they were able to spot tagged DNA sequences that may be important for the development of RA. And they suspect their experimental method can be applied to predict similar risk factors for other common, noninfectious diseases, like type II diabetes and heart ailments.

01/21/2013 - 14:32

A new study by researchers at Karolinska Institutet in Sweden and Johns Hopkins University School of Medicine in the US shows that so-called epigenetic changes in the DNA are involved in causing rheumatoid arthritis, and that these changes can be genetically predetermined. The paper, which is published in the scientific periodical Nature Biotechnology, sheds light on how risk genes can be expressed in disease and why some individuals are affected more readily than others.

10/03/2012 - 13:00

Earlier studies have shown that people with rheumatoid arthritis (RA) are more likely to develop blood clots in the legs or lungs - venous thromboembolism - especially in conjunction with hospitalisation. It has therefore been suggested that people with RA be given routine anticoagulants when admitted to hospital. Researchers at Karolinska Institutet have now shown in a large-scale registry study that although this patient group is indeed more likely to develop thromboembolisms, the risk is different to what was previously feared.