stem cell

UCLA scientists find way to repair mutations in human mitochondria
03/12/2012 - 14:44

Researchers at the UCLA stem cell center and the departments of chemistry and biochemistry and pathology and laboratory medicine have identified, for the first time, a generic way to correct mutations in human mitochondrial DNA by targeting corrective RNAs, a finding with implications for treating a host of mitochondrial diseases.

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Planarian genes that control stem cell biology identified
03/02/2012 - 09:51

Despite their unassuming appearance, the planarian flatworms in Whitehead Institute Member Peter Reddien’s lab are revealing powerful new insights into the biology of stem cells—insights that may eventually help such cells deliver on a promising role in regenerative medicine. 

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Encouraging Results with Stem Cell Transplant for Brain Injury
02/01/2012 - 11:41

Experiments in brain-injured rats show that stem cells injected via the carotid artery travel directly to the brain, where they greatly enhance functional recovery, reports a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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Scientists at Genome Institute of Singapore Identify Stem Cell Key to Lung Regeneration
10/30/2011 - 21:47

Scientists at A*STAR’S Genome Institute of Singapore (GIS) and Institute of Molecular Biology (IMB), have made a breakthrough discovery in the understanding of lung regeneration. Their research showed for the first time that distal airway stem cells (DASCs), a specific type of stem cells in the lungs, are involved in forming new alveoli to replace and repair damaged lung tissue, providing a firm foundation for understanding lung regeneration. 

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Clean correction of a patient's genetic mutation
10/12/2011 - 22:00

New gene therapy methods accurately correct mutation in patient's stem cells, bringing personalized cell therapies one step closer. For the first time, scientists have cleanly corrected a human gene mutation in a patient's stem cells. The result,reported in Nature on Wednesday 12 October, brings the possibility of patient-specific therapies closer to becoming a reality.

 
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UCLA scientists complete first mapping of molecule found in human embryonic stem cells
07/21/2011 - 16:21

Stem cell researchers at UCLA have generated the first genome-wide mapping of a DNA modification called 5-hydroxymethylcytosine (5hmC) in embryonic stem cells, and discovered that it is predominantly found in genes that are turned on, or active.

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