tumor

Scientists make mouse model of human cancer, demonstrate cure
03/05/2013 - 12:37

 UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

 

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'NanoVelcro' device to grab single cancer cells from blood further refined
02/23/2013 - 09:43

Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients' tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis.

 

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Scientists Find Promising New Approach to Preventing Progression of Breast Cancer
02/17/2013 - 11:08

Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode—an issue with profound implications for treatment. Now a group from The Scripps Research Institute (TSRI) has identified a mechanism through which mitochondria, the powerhouses of a cell, control tumor aggressiveness. Based on their findings, the team developed a simple treatment that inhibits cancer progression and prolongs life when tested in mice.

 

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Scientists Create Method to Personalize Chemotherapy Drug Selection
02/14/2013 - 14:36

In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors. If the technique is successful in further studies, it could replace current laboratory tests to optimize drug selection that have proven technically challenging, of limited use, and slow, the researchers say.

 

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Tumour blood vessels prevent the spread of cancer cells
02/12/2013 - 09:34

A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team suggests that drugs should be developed to strengthen the blood vessels protective function.

 

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New Computational Pipeline Analyzes Tumor Images, May Help Predict Response to Cancer Therapy
02/04/2013 - 13:05

How’s this for big data: A whole-slide image of a tumor section can be ten billion pixels. There can be thousands of such images in the tumor cohorts maintained by The Cancer Genome Atlas project, which are collected from a large pool of patients.

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