liver

Scientists Develop New Compound SR9238 that Reverses Fatty Liver Disease
12/20/2012 - 10:38

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed the first synthetic compound that can reverse the effects of a serious metabolic condition known as fatty liver disease. True to its name, the disease involves an abnormal buildup of fat in the liver.

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Synthetic liver enzyme could result in more effective drugs with fewer side effects
10/09/2012 - 14:33

Researchers based at Princeton University reported in the journal Science that they created a synthetic enzyme that acts as a catalyst to replace certain hydrogen atoms of a drug molecule with fluorine atoms. This swap stabilizes the molecule and makes it resistant to the liver enzymes that can inactivate a drug or create toxic byproducts.

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Liver Stiffness Predicts Liver Failure, Cancer and Mortality in Cirrhotic Patients Coinfected with HIV/AIDS and HCV
07/10/2012 - 14:38

Researchers from Spain established that liver stiffness, measured by transient elastography (TE), is an independent predictor of liver failure, hepatocellular carcinoma (HCC), and mortality in cirrhotic patients coinfected with the human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS), and hepatitis C virus (HCV).

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VCU researchers identify changes in cholesterol metabolic pathways
06/07/2012 - 15:28

A new study from the Virginia Commonwealth University School of Medicine has identified molecular changes responsible for abnormal cholesterol production and metabolism in the livers of patients with a common liver condition, and these changes may explain the severity of a patient's liver disease and risks to their heart health.

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Genetic test identifies eye cancer tumors likely to spread
05/14/2012 - 18:51

Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver.

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Researchers unravel genetic mechanism of fatty liver disease in obese children
03/26/2012 - 22:36

Obese youths with particular genetic variants may be more prone to fatty liver disease, a leading cause of chronic liver disease in children and adolescents in industrialized countries, according to new findings by Yale School of Medicine researchers.

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