prostate cancer

04/30/2014 - 13:55

Numerous studies have suggested a relationship between cardiovascular disease risk factors and prostate cancer. A new study by researchers at the University of California, San Diego School of Medicine, with colleagues in Norway, significantly refines the association, highlighting genetic risk factors associated with low density lipoprotein (LDL) cholesterol and triglycerides as key players and identifying 17 related gene loci that make risk contributions to levels of these blood lipids and to prostate cancer.

 

03/18/2014 - 11:49

The microRNA miR-34 cooperates with the ‘guardian of the genome’ p53 to function as a tumor suppressor in a mouse model of prostate cancer. The mechanism involves joint p53 and miR-34 mediated control of a cancer-promoting gene called MET. These are the findings of a new study published in the journal Cell Reports from researchers in Germany and the USA. This study clarifies how miR-34 can be used as an important therapeutic agent for prostate cancer as it enters phase I clinical trials.

 

02/27/2014 - 09:25

Surgical treatment offers better survival rates than radiotherapy for men with clinically localised prostate cancer, according to one of the largest studies of its type. Researchers in Oxford, Stockholm, and the Netherlands compared data from more than 34,000 patients in Sweden over a 15-year period.

 

02/05/2014 - 10:22

New evidence reported by researchers at Roswell Park Cancer Institute (RPCI) lends support to the hypothesis that the SSeCKS/AKAP12 gene is a key inhibitor of prostate cancer metastasis. The data are some of the first to demonstrate this dynamic in transgenic animal models, with promising implications for development of targeted therapies for prostate cancer and perhaps for other solid-tumor cancers.

 

12/09/2013 - 21:30

Zinc, an essential nutrient, is found in every tissue in the body. The vast majority of the metal ion is tightly bound to proteins, helping them to perform biological reactions. Tiny amounts of zinc, however, are only loosely bound, or “mobile,” and thought to be critical for proper function in organs such as the brain, pancreas, and prostate gland. Yet the exact roles the ion plays in biological systems are unknown.

 

10/18/2013 - 14:07

An ethically dubious medical research study from the 1950s and 60s, known as the “Bowery series,” foreshadowed and shared commonalities with prostate cancer screening and treatment measures as they are carried out today, argues University of Pennsylvania physician and historian Robert Aronowitz in two new publications.