10/08/2012 - 15:17

Rice University biochemist James McNew took a risk and changed his lab's model organism from yeast to fruit flies to study a key protein that's been linked to hereditary spastic paraplegia. The gamble paid off with a new grant from the National Institutes of Health.

05/07/2012 - 06:37

Scientists at the Research Institute of Molecular Pathology in Vienna discover and elucidate the function of conserved cell division proteins in yeast. The adult human body consists of trillions of cells. Cell proliferation is accomplished by means of cell division in which an existing cell serves as the exact blueprint for its progeny. This process follows the same basic principles in all higher organisms.

02/19/2012 - 22:55

In a standard biology textbook, cells tend to look more or less the same from all sides. But in real life cells have fronts and backs, tops and bottoms, and they orient many of their structures according to this polarity explaining, for example, why yeast cells bud at one end and not the other.

02/17/2012 - 22:53

 Prions, the much-maligned proteins most commonly known for causing “mad cow” disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and eventually become “hard-wired” into the genome, contributing to evolutionary change.

02/15/2012 - 10:22

Personal change can redefine or even save your life—especially if you are one of a hundred yeast cell clones clinging to the skin of a grape that falls from a sun-drenched vine into a stagnant puddle below. By altering which genes are expressed, cells with identical genomes like these yeast clones are able to survive in new environments or even perform different roles within a multicellular organism.

01/16/2012 - 15:29

With one simple experiment, University of Illinois chemists have debunked a widely held misconception about an often-prescribed drug. Led by chemistry professor and Howard Hughes Medical Institute early career scientist Martin Burke, the researchers demonstrated that the top drug for treating systemic fungal infections works by simply binding to a lipid molecule essential to yeast's physiology, a finding that could change the direction of drug development endeavors and could lead to better treatment not only for microbial infections but also for diseases caused by ion channel deficiencies.