immunity

06/24/2014 - 20:52

In the complex environment of a spinal cord injury, researchers have found that immune cells in the central nervous system of elderly mice fail to activate an important signaling pathway, dramatically lowering chances for repair after injury.

06/05/2014 - 11:00

Psoriasis is a common, long-lasting disease that causes itchy or sore patches of thick, red skin with silvery scales. Environmental contaminants can trigger psoriasis and other autoimmune disorders, and it is thought that a protein called the aryl hydrocarbon receptor (AhR), which senses environmental toxins, could play a role. A study published by Cell Press on June 5 in the journal Immunity shows that the severity of inflammation associated with psoriasis is unexpectedly suppressed by AhR. The findings suggest that stimulation of AhR could improve symptoms and may represent a novel strategy for treating chronic inflammatory skin disorders.

04/22/2014 - 09:13

When humans are suffering from an infection, it is common to become fatigued and to want to sleep more than usual. Two studies on fruit flies published online ahead of print in the journal Sleep suggest that this instinct should be followed. The studies from researchers in the University of Pennsylvania show that sleep is important in increasing resistance to infection and promoting survival.

 

12/09/2013 - 10:15

High-density lipoprotein (HDL), known colloquially as "good cholesterol", protects against dangerous deposits in the arteries. An important function of HDL is its anti-inflammatory properties. An international research team at the Institute of Innate Immunity at the University Hospital of Bonn and the LIMES Institute at the University of Bonn has identified a central switch by which HDL controls the inflammatory response. The results are presented in the current issue of "Nature Immunology".

 

09/04/2013 - 12:38

People living in industrialised countries may be more likely to develop Alzheimer’s due to greatly reduced contact with bacteria, viruses and other microorganisms - which can lead to problems with immune development and increased risk of dementia, suggests a new study.

 

08/08/2013 - 15:21

An investigational malaria vaccine has been found to be safe, to generate an immune system response, and to offer protection against malaria infection in healthy adults, according to the results of an early-stage clinical trial published Aug. 8 in the journal Science.